Invented by Lidor GIL, Ronit RIMON KNOPF, Noa MATARASSO, David Panik, Limor Poraty-Gavra, Ehud KATZ, Hagai Karchi, Evogene Ltd

The market for isolated polynucleotides, polypeptides, and methods of using them for increasing plant yield and/or agricultural characteristics is experiencing significant growth and innovation. As the global population continues to expand, the demand for food production is increasing, and farmers are seeking new ways to enhance crop productivity and improve agricultural traits. This has led to the development and adoption of advanced biotechnological tools and techniques in the agricultural sector. Isolated polynucleotides and polypeptides are key components of genetic engineering and biotechnology. Polynucleotides refer to DNA or RNA molecules, while polypeptides are chains of amino acids that form proteins. These molecules can be modified or introduced into plants to enhance specific traits, such as disease resistance, drought tolerance, and nutrient uptake. By manipulating the genetic makeup of plants, scientists can develop crops that are more resilient, productive, and sustainable. The market for isolated polynucleotides, polypeptides, and their methods of use is driven by several factors. Firstly, the need to increase agricultural productivity to meet the growing demand for food is a primary driver. With limited arable land and changing climatic conditions, farmers are turning to biotechnology to optimize crop yields and minimize losses. The use of isolated polynucleotides and polypeptides allows for targeted genetic modifications that can significantly improve plant performance and yield potential. Secondly, the increasing awareness and acceptance of genetically modified organisms (GMOs) in agriculture have contributed to the market growth. While GMOs have faced controversy in the past, advancements in biotechnology and stringent regulatory frameworks have led to greater confidence in their safety and efficacy. Farmers and consumers are recognizing the benefits of genetically modified crops, such as reduced pesticide use, improved nutritional content, and enhanced resistance to pests and diseases. Furthermore, the rapid advancements in genetic engineering technologies have fueled innovation in the market. Techniques like CRISPR-Cas9, RNA interference, and gene stacking have revolutionized the precision and efficiency of genetic modifications. These tools allow scientists to precisely edit or introduce specific genes into plants, resulting in more predictable and desirable outcomes. As these technologies become more accessible and cost-effective, the market for isolated polynucleotides and polypeptides is expected to expand further. The market for isolated polynucleotides, polypeptides, and methods of using them for increasing plant yield and/or agricultural characteristics is highly competitive and diverse. Numerous biotechnology companies, research institutions, and agricultural organizations are actively involved in developing and commercializing these technologies. They offer a wide range of products and services, including genetically modified seeds, gene editing tools, and consulting services for crop improvement. In addition to the commercial sector, governments and regulatory bodies play a crucial role in shaping the market. They establish guidelines and regulations to ensure the safety, ethical use, and proper labeling of genetically modified crops. These regulations vary across countries, and compliance with local regulations is essential for market players to gain acceptance and access to different markets. Overall, the market for isolated polynucleotides, polypeptides, and methods of using them for increasing plant yield and/or agricultural characteristics is poised for significant growth. The increasing demand for food, coupled with advancements in biotechnology and genetic engineering, presents immense opportunities for innovation and market expansion. As the agricultural sector continues to embrace these technologies, the market will witness further advancements and contribute to sustainable and efficient food production.

The Evogene Ltd invention works as follows

The invention provides isolated polypeptides that are at least 80 percent identical to SEQ NOs 710-1153, 9276-15726 and 1-709, as well as isolated polynucleotides, which are also at least 80 percent identical to SEQ NOs 1157-9275 and 1-709, nucleic acids containing same, transgenic cell expressing the same, transgenic plant expressing the same and methods of using them to increase yield, abiotic stresses tolerance, growth rate and biomass,

Background for Isolated Polynucleotides, Polypeptides and Methods of Using Same for Increasing Plant Yield and/or Agricultural Characteristics

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According to some embodiments, there is a method for increasing yields, growth rates, biomass and vigor of plants, as well as their oil content. This can be achieved by expressing in the plant a polynucleotide containing the nucleic acids sequences selected from SEQ ID Nos. 4-86, 100-312, 395-475, 477, 494-696, 704-709, 1157-42445, 4247-8375, 8387

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According to some embodiments of this invention, an isolated polynucleotide is provided that contains the nucleic acids sequences selected from the following SEQ ID Nos: 4-86 88, 100-312 320-389 391, 395-475 477, 489-696 704-709 1157-4245 4247-8375 8387-8683 and 8686-9275.

According to some embodiments, a nucleic-acid construct is provided that contains the isolated polynucleotide from some embodiments and a promoter used to direct transcription of the nucleic-acid sequence in the host cell.

The

The following amino acid sequences are included in some embodiments of this invention: SEQ

According to some embodiments, a plant cell is provided that exogenously expresses the polynucleotide or nucleic acid of certain embodiments.

According to some embodiments, a plant cell expressing exogenously the polypeptide in some embodiments is provided.

The invention includes a nucleic acid that encodes an amino-acid sequence from the following list:

According to certain embodiments of the present invention, the nucleic acids sequence is chosen from the following SEQ ID Nos: 4-86, 88, 100-312, 395-475, 477, 489-696, 704-709, 1157-4245, 4247-8375, 8387 – 8683, and 8686-9275.

According to certain embodiments of the present invention, the polynucleotide is composed of the nucleic acids sequences selected from the following SEQ ID Nos: 4-86, 88, 100-312, 395-475, 477, 489-696, 704-709, 1157-4245, 4247-8375, 8387 – 8683, and 8686-9275.

The invention includes some embodiments where the nucleic acids encode the amino acid sequence from the following group: S

According to certain embodiments of the present invention, a plant cell is a part of a living plant.

According to certain embodiments of the present invention, the method also comprises growing the plant that expresses the exogenous nucleotide in the presence of abiotic stress.

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