Invented by Jiang Liu, Michael Richard Johnston, Xiao Yu Wu, Individual

The lymphatic system plays a crucial role in the human body, as it helps to remove waste and toxins from the body. However, when this system is not functioning properly, it can lead to a range of health issues, including lymphedema, infections, and even cancer. As a result, there is a growing market for methods, devices, and methods for lymphatic targeting. One of the most promising areas of research in this field is the development of new drugs and therapies that target the lymphatic system. For example, researchers are exploring the use of nanoparticles to deliver drugs directly to the lymphatic system, which could help to improve the effectiveness of treatments for lymphedema and other conditions. Another area of focus is the development of new devices and tools for lymphatic targeting. For example, there are now specialized massage tools that are designed to stimulate the lymphatic system and promote lymphatic drainage. There are also compression garments and pumps that can help to improve lymphatic flow and reduce swelling. In addition to these methods and devices, there are also a number of lifestyle changes that can help to support lymphatic health. For example, regular exercise, a healthy diet, and stress reduction techniques like meditation and yoga can all help to improve lymphatic function and reduce the risk of lymphatic-related health issues. Overall, the market for methods, devices, and methods for lymphatic targeting is growing rapidly, as more and more people become aware of the importance of this system to overall health and well-being. Whether through new drugs and therapies, specialized devices and tools, or lifestyle changes, there are many ways to support lymphatic health and improve overall health and wellness.

The Individual invention works as follows

The invention concerns an implantable device that comprises a biocompatible, biodegradable matrix immured with a bioactive compound suitable for selectively targeting lymphatic systems. The bioactive complex includes one or more particle-forming materials and one/more bioactive agents. Further, the invention addresses methods for preparing and using the implantable device.

Background for Methods, devices and methods for lymphatic targeting




Cell Lines and Animals.

Example 1 – Intrapleural lymphatic distribution of various species of Particulates

Example 2 – Size Impact on Lymphatic Distribution after Intrapleural Administration

Example 3 – Synthesis and Characterization PLGA, PPLGA-PTX Microspheres

Preparation and loading of PLGA microparticulates with Paclitaxel Loaded PLGA

Characterization Paclitaxel-Loaded PLGA microparticles

Particle size and Morphology

Determination Of Drug Content In The PLGA Particles.

In Vitro Drug Delivery of PLGA -PTX Microspheres


Microsphere Preparation Efficiency and Encapsulation Efficiency

Morphological Characteristics for the Microspheres

Particle Size Distribution

Example 4 – Synthesis and Characterization Gelatin Sponge Containing microparticulates

Preparation Gelatin-Alginate Sponge Containing Different Microspheres

Morphology Of Gelatin Sponge Containing Microparticulates

Preparation Crosslinked Gelatin Sponges Containing Microspheres of PLGA/PTX

Assay of In Vitro Drug Release

Click here to view the patent on Google Patents.